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Grape Seed Extract

grapes

Grape Seed Extract

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Introduction

This fact sheet provides basic information about grape seed extract—uses, potential side effects, and resources for more information. The grape seeds used to produce grape seed extract are generally obtained from wine manufacturers. The leaves and fruit of the grape have been used medicinally since ancient Greece.

Common Name—grape seed extract

Latin NameVitis vinifera

What It Is Used For

  • Grape seed extract is used for conditions related to the heart and blood vessels, such as atherosclerosis (hardening of the arteries), high blood pressure, high cholesterol, and poor circulation.
  • Other reasons for the use of grape seed extract include complications related to diabetes, such as nerve and eye damage; vision problems, such as macular degeneration (which can cause blindness); and swelling after an injury or surgery.
  • Grape seed extract is also used for cancer prevention and wound healing.

How It Is Used

Grape seed extract is prepared from the seed of grapes. It is available in capsule and tablet forms.

What the Science Says

  • Laboratory studies have shown that grape seed contains antioxidants-substances that prevent cell damage caused by free radicals, which are highly reactive molecules that can damage cell function. However, it is still unclear how grape seed might affect human health.
  • Grape seed extract has shown some beneficial antioxidant effects in preliminary clinical trials. However, few trials have looked at specific diseases or conditions, and little scientific evidence is available.
  • A study funded by the National Cancer Institute (NCI) found that grape seed extract did not reduce the hardening of breast tissue that can occur after radiation therapy for breast cancer.
  • NCI is also funding studies evaluating whether grape seed extract is effective in preventing breast and prostate cancers.
  • NCCAM is studying whether the action of grape seed extract and its components may benefit the heart or have protective effects in the brain.

Side Effects and Cautions

  • Grape seed extract is generally well tolerated when taken by mouth. It has been used safely for up to 8 weeks in clinical trials.
  • Side effects that have been reported most often include headache; a dry, itchy scalp; dizziness; and nausea.
  • The interactions between grape seed extract and medicines or other supplements have not been carefully studied.
  • Tell your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

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Lavender

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Lavender

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Introduction

This fact sheet provides basic information about the herb lavender—common names, uses, potential side effects, and resources for more information. Lavender is native to the Mediterranean region. It was used in ancient Egypt as part of the process for mummifying bodies. Lavender’s use as a bath additive originated in Persia, Greece, and Rome. The herb’s name comes from the Latin lavare, which means “to wash.”

Common Names–lavender, English lavender, garden lavender

Latin NamesLavandula angustifolia

What It Is Used For

  • Historically, lavender was used as an antiseptic and for mental health purposes.
  • Today, the herb is used for conditions such as anxiety, restlessness, insomnia, and depression.
  • Lavender is also used for headache, upset stomach, and hair loss.

How It Is Used

  • Lavender is most commonly used in aromatherapy, in which the scent of the essential oil from the flowers is inhaled.
  • The essential oil can also be diluted with another oil and applied to the skin.
  • Dried lavender flowers can be used to make teas or liquid extracts that can be taken by mouth.

What the Science Says

  • There is little scientific evidence of lavender’s effectiveness for most health uses.
  • Small studies on lavender for anxiety show mixed results.
  • Some preliminary results indicate that lavender oil, combined with oils from other herbs, may help with hair loss from a condition called alopecia areata.

Side Effects and Cautions

  • Topical use of diluted lavender oil or use of lavender as aromatherapy is generally considered safe for most adults. However, applying lavender oil to the skin can cause irritation.
  • Lavender oil may be poisonous if taken by mouth.
  • When lavender teas and extracts are taken by mouth, they may cause headache, changes in appetite, and constipation.
  • Using lavender with sedative medications may increase drowsiness.
  • Tell your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

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Bilberry

bilberry

Bilberry

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Introduction

This fact sheet provides basic information about bilberry—common names, uses, potential side effects, and resources for more information. Bilberry is a relative of the blueberry, and its fruit is commonly used to make pies and jams. It has been used for nearly 1,000 years in traditional European medicine. Bilberry grows in North America, Europe, and northern Asia.

Common Names—bilberry, European blueberry, whortleberry, huckleberry

Latin NamesVaccinium myrtillus

What It Is Used For

  • Historically, bilberry fruit was used to treat diarrhea, scurvy, and other conditions.
  • Today, the fruit is used to treat diarrhea, menstrual cramps, eye problems, varicose veins, venous insufficiency (a condition in which the veins do not efficiently return blood from the legs to the heart), and other circulatory problems.
  • Bilberry leaf is used for entirely different conditions, including diabetes.

How It Is Used

The fruit of the bilberry plant can be eaten or made into extracts. Similarly, the leaves of the bilberry plant can be made into extracts or used to make teas.

What the Science Says

  • Some claim that bilberry fruit improves night vision, but clinical studies have not shown this to be true.
  • There is not enough scientific evidence to support the use of bilberry fruit or leaf for any health conditions.

Side Effects and Cautions

  • Bilberry fruit is considered safe. However, high doses of bilberry leaf or leaf extract are considered unsafe due to possible toxic side effects.
  • Tell your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

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Asian Ginseng

aginseng

Asian Ginseng

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Introduction

This fact sheet provides basic information about the herb Asian ginseng—common names, uses, potential side effects, and resources for more information. Asian ginseng is native to China and Korea and has been used in various systems of medicine for many centuries. Asian ginseng is one of several types of true ginseng (another is American ginseng, Panax quinquefolius). An herb called Siberian ginseng or eleuthero (Eleutherococcus senticosus) is not a true ginseng.

Common Names—Asian ginseng, ginseng, Chinese ginseng, Korean ginseng, Asiatic ginseng

Latin NamePanax ginseng

What It Is Used For

Treatment claims for Asian ginseng are numerous and include the use of the herb to support overall health and boost the immune system. Traditional and modern uses of ginseng include:

  • Improving the health of people recovering from illness
  • Increasing a sense of well-being and stamina, and improving both mental and physical performance
  • Treating erectile dysfunction, hepatitis C, and symptoms related to menopause
  • Lowering blood glucose and controlling blood pressure

How It Is Used

The root of Asian ginseng contains active chemical components called ginsenosides (or panaxosides) that are thought to be responsible for the herb’s medicinal properties. The root is dried and used to make tablets or capsules, extracts, and teas, as well as creams or other preparations for external use.

What the Science Says

  • Some studies have shown that Asian ginseng may lower blood glucose. Other studies indicate possible beneficial effects on immune function.
  • To date, research results on Asian ginseng are not conclusive enough to prove health claims associated with the herb. Only a handful of large clinical trials on Asian ginseng have been conducted. Most studies have been small or have had flaws in design and reporting. Some claims for health benefits have been based only on studies conducted in animals.
  • NCCAM supports studies to better understand the use of Asian ginseng. Areas of recent NCCAM-funded research include Asian ginseng’s interactions with other herbs and drugs and the herb’s potential to treat chronic lung infection, impaired glucose tolerance, and Alzheimer’s disease.

Side Effects and Cautions

  • When taken by mouth, ginseng is usually well tolerated. Some sources suggest that its use be limited to 3 months because of concerns about the development of side effects.
  • The most common side effects are headaches and sleep and gastrointestinal problems.
  • Asian ginseng can cause allergic reactions.
  • There have been reports of breast tenderness, menstrual irregularities, and high blood pressure associated with Asian ginseng products, but these products’ components were not analyzed, so effects may have been due to another herb or drug in the product.
  • Asian ginseng may lower levels of blood sugar; this effect may be seen more in people with diabetes. Therefore, people with diabetes should use extra caution with Asian ginseng, especially if they are using medicines to lower blood sugar or taking other herbs, such as bitter melon and fenugreek, that are also thought to lower blood sugar.
  • Tell your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

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